Dr.Wan-ChenWu Taiwan

Dr. Wan-Chen Wu, is an Attending Physician in the Division of Endocrinology & Metabolism at National Taiwan University Hospital and a Clinical Assistant Professor in Internal Medicine at National Taiwan University College of Medicine. Dr. Wu’s clinical and research focus centers on adrenal disorders, with a particular emphasis on the genetics and molecular subtyping of pheochromocytomas and paragangliomas (PPGL). Her work spans translational genomics and clinical diagnostics to elucidate how germline and somatic variants shape presentation, management, and outcomes. She and collaborators established a clinical genetic testing platform for PPGL in Taiwan, identifying a distinctive SDHD founder variant and highlighting the disorder’s unique parent-of-origin inheritance in the local population. Complementing her genetics research, Dr. Wu has advanced biochemical diagnostics by developing and validating local reference intervals and diagnostic cutoffs for plasma free metanephrines using HPLC-MS/MS - improving the sensitivity of PPGL detection over legacy urine catecholamine assays in Taiwan. Beyond PPGL, her scholarship includes first-author work demonstrating that patients with endogenous Cushing’s syndrome have persistently elevated cancer risk, informing long-term survivorship care. Dr. Wu has been recognized with an International Congress of Endocrinology Travel Fellowship Award and has delivered invited presentations at regional and international endocrine meetings. At AOCE 2026, Dr. Wu will synthesize population-specific genetic insights, founder effects, and parent-of-origin phenomena with state-of-the-art biochemical profiling to outline pragmatic pathways for PPGL diagnosis and risk stratification in diverse Asian cohorts.